Aplikasi Media Terkondisi Sel Punca Mesensimal dalam Terapi Penyakit Degeneratif dan Penyembuhan Luka

Stefani Santi Widhiastuti

Abstract


Penyakit degeneratif seperti stroke, jantung, hipertensi, dan diabetes merupakan penyakit yang banyak dialami seseorang seiring dengan bertambahnya usia. Terapi dengan obat-obatan maupun dengan operasi telah banyak digunakan Namun pada beberapa kasus, hasilnya belum maksimal. Dengan meningkatnya ilmu pengetahuan dan teknologi, sel punca juga dikembangkan sebagai terapi regeneratif, tidak hanya untuk pengobatan penyakit degeneratif namun juga untuk penyembuhan luka akibat trauma fisik maupun penyakit yang lain. Salah satu macam sel punca yang banyak digunakan adalah sel punca mesensimal (SPM). Meskipun sel punca memiliki potensi untuk dikembangkan sebagai terapi penyakit degeneratif dan penyembuhan luka, namun proses diferensiasinya dalam tubuh belum terkontrol dengan maksimal, sehingga banyak peneliti mengembangkan penggunaan media terkondisi sel punca mesensimal (MT-SPM) sebagai terapi alternatif. MT-SPM yang merupakan medium cair tempat tumbuh SPM terbukti memiliki efek serupa dengan SPM, sehingga dapat digunakan dalam terapi penyakit stroke, jantung, diabetes, dan penyembuhan luka.


Keywords


Stem Cell, SPM, MT-SPM, penyakit degeneratif, penyembuhan luka

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DOI: https://doi.org/10.24002/biota.v5i1.2963

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